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Tumor suppressor p16(INK4a) inhibits cancer cell growth by downregulating eEF1A2 through a direct interaction

The tumor suppressor protein p16(INK4a) is a member of the INK4 family of cyclin-dependent kinase (Cdk) inhibitors, which are involved in the regulation of the eukaryotic cell cycle. However, the mechanisms underlying the anti-proliferative effects of p16(INK4a) have not been fully elucidated. Using...

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Detalhes bibliográficos
Main Authors: Lee, Mee-Hyun, Choi, Bu Young, Cho, Yong-Yeon, Lee, Sung-Young, Huang, Zunnan, Kundu, Joydeb Kumar, Kim, Myoung Ok, Kim, Dong Joon, Bode, Ann M., Surh, Young-Joon, Dong, Zigang
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3678409/
https://ncbi.nlm.nih.gov/pubmed/23444377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.113613
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