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Oncolytic virus delivery: from nano-pharmacodynamics to enhanced oncolytic effect

With the advancement of a growing number of oncolytic viruses (OVs) to clinical development, drug delivery is becoming an important barrier to overcome for optimal therapeutic benefits. Host immunity, tumor microenvironment and abnormal vascularity contribute to inefficient vector delivery. A number...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Oncolytic Virother
Hauptverfasser: Yokoda, Raquel, Nagalo, Bolni M, Vernon, Brent, Oklu, Rahmi, Albadawi, Hassan, DeLeon, Thomas T, Zhou, Yumei, Egan, Jan B, Duda, Dan G, Borad, Mitesh J
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5687448/
https://ncbi.nlm.nih.gov/pubmed/29184854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OV.S145262
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