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GPX3 promoter methylation predicts platinum sensitivity in colorectal cancer

Epigenetic control of gene expression is a major determinant of tumor phenotype and has been found to influence sensitivity to individual chemotherapeutic agents. Glutathione peroxidase 3 (GPX3, plasma glutathione peroxidase) is a key component of cellular antioxidant regulation and its gene has bee...

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Detalhes bibliográficos
Publicado no:Epigenetics
Main Authors: Pelosof, Lorraine, Yerram, Sashidhar, Armstrong, Todd, Chu, Nina, Danilova, Ludmila, Yanagisawa, Breann, Hidalgo, Manuel, Azad, Nilofer, Herman, James G.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5687334/
https://ncbi.nlm.nih.gov/pubmed/27918237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2016.1265711
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