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Mouse olfactory bulb methylome and hydroxymethylome maps reveal noncanonical active turnover of DNA methylation

Hydroxylation of 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC) by TET enzymes presents a particular regulatory mechanism in the mammalian brain. However, although methylation and hydroxymethylation of cytosines in non-CpG contexts have been reported, these mechanisms remain poorly underst...

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Publicat a:Epigenetics
Autors principals: Ma, Qin, Lu, Huan, Xu, Ziying, Zhou, Yuanyuan, Ci, Weimin
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5687332/
https://ncbi.nlm.nih.gov/pubmed/28945496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2017.1356958
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