Epigenetic dysregulation of the erythropoietic transcription factor KLF1 and the β-like globin locus in juvenile myelomonocytic leukemia

Increased levels of fetal hemoglobin (HbF) are a hallmark of more than half of the children diagnosed with juvenile myelomonocytic leukemia (JMML). Elevated HbF levels in JMML are associated with DNA hypermethylation of distinct gene promoter regions in leukemic cells. Since the regulation of globin...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Epigenetics
Main Authors: Fluhr, Silvia, Krombholz, Christopher Felix, Meier, Angelina, Epting, Thomas, Mücke, Oliver, Plass, Christoph, Niemeyer, Charlotte M., Flotho, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5687323/
https://ncbi.nlm.nih.gov/pubmed/28749240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2017.1356959
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados