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Investigation of binding behaviour of procainamide hydrochloride with human serum albumin using synchronous, 3D fluorescence and circular dichroism

Interaction of procainamide hydrochloride (PAH) with human serum albumin (HSA) is of great significance in understanding the pharmacokinetic and pharmacodynamic mechanisms of the drug. Multi-spectroscopic techniques were used to investigate the binding mode of PAH to HSA and results revealed the pre...

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Detalhes bibliográficos
Publicado no:J Pharm Anal
Main Authors: Byadagi, Kirthi, Meti, Manjunath, Nandibewoor, Sharanappa, Chimatadar, Shivamurti
Formato: Artigo
Idioma:Inglês
Publicado em: Xi'an Jiaotong University 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5686859/
https://ncbi.nlm.nih.gov/pubmed/29404024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpha.2016.07.004
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