Investigation of binding behaviour of procainamide hydrochloride with human serum albumin using synchronous, 3D fluorescence and circular dichroism

Interaction of procainamide hydrochloride (PAH) with human serum albumin (HSA) is of great significance in understanding the pharmacokinetic and pharmacodynamic mechanisms of the drug. Multi-spectroscopic techniques were used to investigate the binding mode of PAH to HSA and results revealed the pre...

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Vydáno v:J Pharm Anal
Hlavní autoři: Byadagi, Kirthi, Meti, Manjunath, Nandibewoor, Sharanappa, Chimatadar, Shivamurti
Médium: Artigo
Jazyk:Inglês
Vydáno: Xi'an Jiaotong University 2017
Témata:
Original Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5686859/
https://ncbi.nlm.nih.gov/pubmed/29404024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpha.2016.07.004
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