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Anaerobic Mycobacterium tuberculosis Cell Death Stems from Intracellular Acidification Mitigated by the DosR Regulon

Mycobacterium tuberculosis is a strict aerobe capable of prolonged survival in the absence of oxygen. We investigated the ability of anaerobic M. tuberculosis to counter challenges to internal pH homeostasis in the absence of aerobic respiration, the primary mechanism of proton efflux for aerobic ba...

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Detalhes bibliográficos
Publicado no:J Bacteriol
Main Authors: Reichlen, Matthew J., Leistikow, Rachel L., Scobey, Micah S., Born, Sarah E. M., Voskuil, Martin I.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5686587/
https://ncbi.nlm.nih.gov/pubmed/28874407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00320-17
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