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Induction of Antiviral Immune Response through Recognition of the Repeating Subunit Pattern of Viral Capsids Is Toll-Like Receptor 2 Dependent

Although viruses and viral capsids induce rapid immune responses, little is known about viral pathogen-associated molecular patterns (PAMPs) that are exhibited on their surface. Here, we demonstrate that the repeating protein subunit pattern common to most virus capsids is a molecular pattern that i...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Shepardson, Kelly M., Schwarz, Benjamin, Larson, Kyle, Morton, Rachelle V., Avera, John, McCoy, Kimberly, Caffrey, Alayna, Harmsen, Ann, Douglas, Trevor, Rynda-Apple, Agnieszka
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5686532/
https://ncbi.nlm.nih.gov/pubmed/29138299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01356-17
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