Both infection with Pneumocystis and virus-like particle exposure prime pulmonary CD11c(+) cells, facilitating accelerated immune responses to influenza

We show that the intranasal delivery of non-replicative virus-like particles (VLPs), which bear structural, but no antigenic similarities to respiratory pathogens, acted to prime the lungs of mice to facilitate heightened and accelerated primary immune responses to high-dose influenza challenge, thu...

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Detalhes bibliográficos
Main Authors: Richert, Laura E., Rynda-Apple, Agnieszka, Harmsen, Ann L., Han, Soo, Wiley, James A., Douglas, Trevor, Larson, Kyle, Morton, Rachelle V., Harmsen, Allen G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3926668/
https://ncbi.nlm.nih.gov/pubmed/24222381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201343587
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