Fine-tuning and autoregulation of the intestinal determinant and tumor suppressor homeobox gene CDX2 by alternative splicing

On the basis of phylogenetic analyses, we uncovered a variant of the CDX2 homeobox gene, a major regulator of the development and homeostasis of the gut epithelium, also involved in cancer. This variant, miniCDX2, is generated by alternative splicing coupled to alternative translation initiation, an...

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Vydáno v:Cell Death Differ
Hlavní autoři: Balbinot, Camille, Vanier, Marie, Armant, Olivier, Nair, Asmaa, Penichon, Julien, Soret, Christine, Martin, Elisabeth, Saandi, Thoueiba, Reimund, Jean-Marie, Deschamps, Jacqueline, Beck, Felix, Domon-Dell, Claire, Gross, Isabelle, Duluc, Isabelle, Freund, Jean-Noël
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2017
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Original Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5686355/
https://ncbi.nlm.nih.gov/pubmed/28862703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2017.140
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