Oxidative stress-induced S100B accumulation converts myoblasts into brown adipocytes via an NF-κB/YY1/miR-133 axis and NF-κB/YY1/BMP-7 axis

Muscles of sarcopenic people show hypotrophic myofibers and infiltration with adipose and, at later stages, fibrotic tissue. The origin of infiltrating adipocytes resides in fibro-adipogenic precursors and nonmyogenic mesenchymal progenitor cells, and in satellite cells, the adult stem cells of skel...

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Vydáno v:Cell Death Differ
Hlavní autoři: Morozzi, Giulio, Beccafico, Sara, Bianchi, Roberta, Riuzzi, Francesca, Bellezza, Ilaria, Giambanco, Ileana, Arcuri, Cataldo, Minelli, Alba, Donato, Rosario
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2017
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Original Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5686349/
https://ncbi.nlm.nih.gov/pubmed/28885620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2017.132
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