S100B Engages RAGE or bFGF/FGFR1 in Myoblasts Depending on Its Own Concentration and Myoblast Density. Implications for Muscle Regeneration

In high-density myoblast cultures S100B enhances basic fibroblast growth factor (bFGF) receptor 1 (FGFR1) signaling via binding to bFGF and blocks its canonical receptor, receptor for advanced glycation end-products (RAGE), thereby stimulating proliferation and inhibiting differentiation. Here we sh...

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Bibliographic Details
Main Authors: Riuzzi, Francesca, Sorci, Guglielmo, Beccafico, Sara, Donato, Rosario
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3262793/
https://ncbi.nlm.nih.gov/pubmed/22276098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028700
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