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Bidirectional modulation of hippocampal synaptic plasticity by Dopaminergic D4-receptors in the CA1 area of hippocampus

Long-term potentiation (LTP) is the persistent increase in the strength of the synapses. However, the neural networks would become saturated if there is only synaptic strenghthening. Synaptic weakening could be facilitated by active processes like long-term depression (LTD). Molecular mechanisms tha...

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Publicat a:Sci Rep
Autors principals: Navakkode, Sheeja, Chew, Katherine C. M., Tay, Sabrina Jia Ning, Lin, Qingshu, Behnisch, Thomas, Soong, Tuck Wah
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5686203/
https://ncbi.nlm.nih.gov/pubmed/29138490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-15917-1
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