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Bidirectional modulation of hippocampal synaptic plasticity by Dopaminergic D4-receptors in the CA1 area of hippocampus

Long-term potentiation (LTP) is the persistent increase in the strength of the synapses. However, the neural networks would become saturated if there is only synaptic strenghthening. Synaptic weakening could be facilitated by active processes like long-term depression (LTD). Molecular mechanisms tha...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Navakkode, Sheeja, Chew, Katherine C. M., Tay, Sabrina Jia Ning, Lin, Qingshu, Behnisch, Thomas, Soong, Tuck Wah
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5686203/
https://ncbi.nlm.nih.gov/pubmed/29138490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-15917-1
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