US6 Gene Deletion in Herpes Simplex Virus Type 2 Enhances Dendritic Cell Function and T Cell Activation

Herpes simplex virus (HSV) type 1 (HSV-1) and type 2 (HSV-2) produce lifelong infections that are associated with frequent asymptomatic or clinically apparent reactivation. Importantly, HSV express multiple virulence factors that negatively modulate innate and adaptive immune components. Notably, HS...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Retamal-Díaz, Angello, Weiss, Kayla A., Tognarelli, Eduardo I., Freire, Mariela, Bueno, Susan M., Herold, Betsy C., Jacobs, William R., González, Pablo A.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5686121/
https://ncbi.nlm.nih.gov/pubmed/29176979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01523
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