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Impaired GABA(B)-mediated presynaptic inhibition increases excitatory strength and alters short-term plasticity in synapsin knockout mice
Synapsins are a family of synaptic vesicle phosphoproteins regulating synaptic transmission and plasticity. SYN1/2 genes are major epilepsy susceptibility genes in humans. Consistently, synapsin I/II/III triple knockout (TKO) mice are epileptic and exhibit severe impairments in phasic and tonic GABA...
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| 發表在: | Oncotarget |
|---|---|
| Main Authors: | , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Impact Journals LLC
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5685732/ https://ncbi.nlm.nih.gov/pubmed/29163811 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21405 |
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