JAK2 aberrations in childhood B-cell precursor acute lymphoblastic leukemia

JAK2 abnormalities may serve as target for precision medicines in pediatric B-cell precursor acute lymphoblastic leukemia (BCP-ALL). In the current study we performed a screening for JAK2 mutations and translocations, analyzed the clinical outcome and studied the efficacy of two JAK inhibitors in pr...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Steeghs, Elisabeth M.P., Jerchel, Isabel S., de Goffau-Nobel, Willemieke, Hoogkamer, Alex Q., Boer, Judith M., Boeree, Aurélie, van de Ven, Cesca, Koudijs, Marco J., Besselink, Nicolle J.M., de Groot-Kruseman, Hester A., Zwaan, Christian Michel, Horstmann, Martin A., Pieters, Rob, den Boer, Monique L.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5685720/
https://ncbi.nlm.nih.gov/pubmed/29163799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21027
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