IMP2/IGF2BP2 expression, but not IMP1 and IMP3, predicts poor outcome in patients and high tumor growth rate in xenograft models of gallbladder cancer

Overexpression of the oncofetal insulin-like growth factor 2 mRNA-binding protein 2 (IMP2/IGF2BP2) has been described in different cancer types. Gallbladder carcinoma (GBC) is a rare but highly aggressive cancer entity with late clinical detection and poor prognosis. The aim of this study was to inv...

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Publicado en:Oncotarget
Autores principales: Kessler, Sonja M., Lederer, Eva, Laggai, Stephan, Golob-Schwarzl, Nicole, Hosseini, Kevan, Petzold, Johannes, Schweiger, Caroline, Reihs, Robert, Keil, Marlen, Hoffmann, Jens, Mayr, Christian, Kiesslich, Tobias, Pichler, Martin, Kim, Kyung Sik, Rhee, Hyungjin, Park, Young Nyun, Lax, Sigurd, Obrist, Peter, Kiemer, Alexandra K., Haybaeck, Johannes
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5685705/
https://ncbi.nlm.nih.gov/pubmed/29163784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21116
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