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Inhibition of HOX/PBX dimer formation leads to necroptosis in acute myeloid leukemia cells
The HOX genes encode a family of transcription factors that have key roles in both development and malignancy. Disrupting the interaction between HOX proteins and their binding partner, PBX, has been shown to cause apoptotic cell death in a range of solid tumors. However, despite HOX proteins playin...
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| 出版年: | Oncotarget |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Impact Journals LLC
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5685692/ https://ncbi.nlm.nih.gov/pubmed/29163771 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20023 |
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