Cholesterol Promotes Protein Binding by Affecting Membrane Electrostatics and Solvation Properties

Binding of the retroviral structural protein Gag to the cellular plasma membrane is mediated by the protein’s matrix (MA) domain. Prominent among MA-PM interactions is electrostatic attraction between the positively charged MA domain and the negatively charged plasma membrane inner leaflet. Previous...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Biophys J
Autori principali: Doktorova, Milka, Heberle, Frederick A., Kingston, Richard L., Khelashvili, George, Cuendet, Michel A., Wen, Yi, Katsaras, John, Feigenson, Gerald W., Vogt, Volker M., Dick, Robert A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Biophysical Society 2017
Soggetti:
Membranes
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5685651/
https://ncbi.nlm.nih.gov/pubmed/29117524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.08.055
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