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HIV-1 Gag protein can sense the cholesterol and acyl chain environment in model membranes

Membrane binding of the HIV-1 group-specific antigen (Gag) structural protein, a critical step in viral assembly at the plasma membrane, is mediated by the myristoylated, highly basic matrix (MA) domain, which interacts with negatively charged lipids in the inner leaflet. According to a popular mode...

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Bibliographische Detailangaben
Hauptverfasser: Dick, Robert A., Goh, Shih Lin, Feigenson, Gerald W., Vogt, Volker M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3503231/
https://ncbi.nlm.nih.gov/pubmed/23010924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1209408109
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