Bioequivalence between innovator and generic tacrolimus in liver and kidney transplant recipients: A randomized, crossover clinical trial

BACKGROUND: Although the generic drug approval process has a long-term successful track record, concerns remain for approval of narrow therapeutic index generic immunosuppressants, such as tacrolimus, in transplant recipients. Several professional transplant societies and publications have generated...

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Veröffentlicht in:PLoS Med
Hauptverfasser: Alloway, Rita R., Vinks, Alexander A., Fukuda, Tsuyoshi, Mizuno, Tomoyuki, King, Eileen C., Zou, Yuanshu, Jiang, Wenlei, Woodle, E. Steve, Tremblay, Simon, Klawitter, Jelena, Klawitter, Jost, Christians, Uwe
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2017
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5685573/
https://ncbi.nlm.nih.gov/pubmed/29135993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.1002428
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