Lipoprotein(a)-Associated Molecules Are Prominent Components in Plasma and Valve Leaflets in Calcific Aortic Valve Stenosis

The LPA gene is the only monogenetic risk factor for calcific aortic valve stenosis (CAVS). Oxidized phospholipids (OxPL) and lysophosphatidic acid generated by autotaxin (ATX) from OxPL are pro-inflammatory. Aortic valve leaflets categorized pathologically from both ATX–apolipoprotein B and ATX–apo...

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Detalles Bibliográficos
Publicado en:JACC Basic Transl Sci
Autores principales: Torzewski, Michael, Ravandi, Amir, Yeang, Calvin, Edel, Andrea, Bhindi, Rahul, Kath, Stefan, Twardowski, Laura, Schmid, Jens, Yang, Xiaohong, Franke, Ulrich F.W., Witztum, Joseph L., Tsimikas, Sotirios
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2017
Materias:
CLINICAL RESEARCH
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5685511/
https://ncbi.nlm.nih.gov/pubmed/29147686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacbts.2017.02.004
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