Lipoprotein(a)-Associated Molecules Are Prominent Components in Plasma and Valve Leaflets in Calcific Aortic Valve Stenosis

The LPA gene is the only monogenetic risk factor for calcific aortic valve stenosis (CAVS). Oxidized phospholipids (OxPL) and lysophosphatidic acid generated by autotaxin (ATX) from OxPL are pro-inflammatory. Aortic valve leaflets categorized pathologically from both ATX–apolipoprotein B and ATX–apo...

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Bibliografiske detaljer
Udgivet i:JACC Basic Transl Sci
Main Authors: Torzewski, Michael, Ravandi, Amir, Yeang, Calvin, Edel, Andrea, Bhindi, Rahul, Kath, Stefan, Twardowski, Laura, Schmid, Jens, Yang, Xiaohong, Franke, Ulrich F.W., Witztum, Joseph L., Tsimikas, Sotirios
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2017
Fag:
CLINICAL RESEARCH
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5685511/
https://ncbi.nlm.nih.gov/pubmed/29147686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacbts.2017.02.004
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