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Calculation of a First-In-Man Dose of 7-O-Succinyl Macrolactin A Based on Allometric Scaling of Data from Mice, Rats, and Dogs

7-O-Succinyl macrolactin A (SMA) exerts several pharmacological effects including anti-bacterial, anti-inflammation, and anti-cancer activities. Recently, SMA has been extensively evaluated as an anti-cancer drug. Thus, the objectives of the present study were to characterise the pharmacokinetics of...

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Vydáno v:Biomol Ther (Seoul)
Hlavní autoři: Noh, Keumhan, Kang, Wonku
Médium: Artigo
Jazyk:Inglês
Vydáno: The Korean Society of Applied Pharmacology 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5685435/
https://ncbi.nlm.nih.gov/pubmed/28274094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4062/biomolther.2016.192
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