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Precision medicine in heritable cancer: when somatic tumour testing and germline mutations meet

Cancer is among the leading causes of death and disfigurement worldwide with an estimated global incidence of 14 million and ~8.2 million cancer-related deaths per annum. An estimated 5–10% of all cancers are hereditary, meaning a single gene mutation contributed to development of the cancer. In oth...

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Detalhes bibliográficos
Publicado no:NPJ Genom Med
Main Authors: Ngeow, Joanne, Eng, Charis
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5685292/
https://ncbi.nlm.nih.gov/pubmed/29263804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npjgenmed.2015.6
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