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Autoimmune response to AGE modified human DNA: Implications in type 1 diabetes mellitus()
AIMS: Non-enzymatic glycation of DNA both in vivo and in vitro results in generation of free radicals, known as glycoxidation. Glycoxidation leads to structural perturbation of DNA resulting in generation of neo-antigenic epitopes having implication in autoimmune disorders like diabetes mellitus. In...
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| Publicado no: | J Clin Transl Endocrinol |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5685016/ https://ncbi.nlm.nih.gov/pubmed/29159085 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcte.2014.05.002 |
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