Autoimmune response to AGE modified human DNA: Implications in type 1 diabetes mellitus()

AIMS: Non-enzymatic glycation of DNA both in vivo and in vitro results in generation of free radicals, known as glycoxidation. Glycoxidation leads to structural perturbation of DNA resulting in generation of neo-antigenic epitopes having implication in autoimmune disorders like diabetes mellitus. In...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Clin Transl Endocrinol
Päätekijät: Ahmad, Saheem, Uddin, Moin, Habib, Safia, Shahab, Uzma, Alam, Khursheed, Ali, Asif
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Elsevier 2014
Aiheet:
Research Paper
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5685016/
https://ncbi.nlm.nih.gov/pubmed/29159085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcte.2014.05.002
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