Effects of mTOR inhibition on cardiac and adipose tissue pathology and glucose metabolism in rats with metabolic syndrome

The mammalian target of rapamycin (mTOR) is a regulator of metabolism and is implicated in pathological conditions such as obesity and diabetes. We aimed to investigate the role of mTOR in obesity. A new animal model of metabolic syndrome (MetS), named DahlS.Z‐Lepr (fa)/Lepr (fa) (DS/obese) rats was...

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Vydáno v:Pharmacol Res Perspect
Hlavní autoři: Uchinaka, Ayako, Yoneda, Mamoru, Yamada, Yuichiro, Murohara, Toyoaki, Nagata, Kohzo
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2017
Témata:
Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5684863/
https://ncbi.nlm.nih.gov/pubmed/28805979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.331
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