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Effects of mTOR inhibition on cardiac and adipose tissue pathology and glucose metabolism in rats with metabolic syndrome

The mammalian target of rapamycin (mTOR) is a regulator of metabolism and is implicated in pathological conditions such as obesity and diabetes. We aimed to investigate the role of mTOR in obesity. A new animal model of metabolic syndrome (MetS), named DahlS.Z‐Lepr (fa)/Lepr (fa) (DS/obese) rats was...

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Detalhes bibliográficos
Publicado no:Pharmacol Res Perspect
Main Authors: Uchinaka, Ayako, Yoneda, Mamoru, Yamada, Yuichiro, Murohara, Toyoaki, Nagata, Kohzo
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5684863/
https://ncbi.nlm.nih.gov/pubmed/28805979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.331
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