EZH2 suppression in glioblastoma shifts microglia toward M1 phenotype in tumor microenvironment

BACKGROUND: Glioblastoma multiforme (GBM) induces tumor immunosuppression through interacting with tumor-infiltrating microglia or macrophages (TAMs) with an unclear pathogenesis. Enhancer of zeste homolog 2 (EZH2) is abundant in GBM samples and cell lines and is involved in GBM proliferation, cell...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Neuroinflammation
Egile Nagusiak: Yin, Yatao, Qiu, Shuwei, Li, Xiangpen, Huang, Bo, Xu, Yun, Peng, Ying
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2017
Gaiak:
Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5684749/
https://ncbi.nlm.nih.gov/pubmed/29132376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-017-0993-4
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