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EZH2 suppression in glioblastoma shifts microglia toward M1 phenotype in tumor microenvironment
BACKGROUND: Glioblastoma multiforme (GBM) induces tumor immunosuppression through interacting with tumor-infiltrating microglia or macrophages (TAMs) with an unclear pathogenesis. Enhancer of zeste homolog 2 (EZH2) is abundant in GBM samples and cell lines and is involved in GBM proliferation, cell...
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| Publicado no: | J Neuroinflammation |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5684749/ https://ncbi.nlm.nih.gov/pubmed/29132376 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-017-0993-4 |
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