IL-21 Therapy Controls Immune Activation and Maintains Antiviral CD8(+) T Cell Responses in Acute Simian Immunodeficiency Virus Infection

Human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) replicate during acute infection in lymphocytes of the gastrointestinal tract, before disseminating systemically. Localized replication and associated loss of gut-resident CD4(+) T cells occur regardless of the portal of entr...

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Bibliografiska uppgifter
I publikationen:AIDS Res Hum Retroviruses
Huvudupphovsmän: Méndez-Lagares, Gema, Lu, Ding, Merriam, David, Baker, Christopher A., Villinger, François, Van Rompay, Koen K. A., McCune, Joseph M., Hartigan-O'Connor, Dennis J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Mary Ann Liebert, Inc. 2017
Ämnen:
Immunology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5684667/
https://ncbi.nlm.nih.gov/pubmed/29140110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/aid.2017.0160
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