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Essential role of mitochondrial Stat3 in p38(MAPK) mediated apoptosis under oxidative stress
Stat3 is an oncogene, frequently associated with malignant transformation. A body of evidence implicates that phospho-Stat3(Y705) contributes to its nucleic translocation, while phospho-Stat3(S727) leads to the accumulation in mitochondria. Both are of importance for tumor cell proliferation. In com...
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| Publicado en: | Sci Rep |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5684365/ https://ncbi.nlm.nih.gov/pubmed/29133922 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-15342-4 |
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