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Site-specific phosphorylation regulates the structure and function of an intrinsically disordered domain of the glucocorticoid receptor

Intrinsically disordered (ID) regions of the transcription factor proteins have much larger frequency of phosphorylation sites than ordered regions, suggesting an important role in their regulatory capacity. Consistent with this phenomenon, most of the functionally known phosphorylation sites in the...

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Publicat a:Sci Rep
Autors principals: Khan, Shagufta H., McLaughlin, William A., Kumar, Raj
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5684351/
https://ncbi.nlm.nih.gov/pubmed/29133811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-15549-5
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