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In Vitro Drug Release After Crushing: Evaluation of Xtampza(®) ER and Other ER Opioid Formulations

BACKGROUND AND OBJECTIVE: Extended-release (ER) opioids are associated with high rates of abuse. Recreational opioid users often manipulate ER formulations to achieve a high plasma concentration in a short amount of time, resulting in a more rapid and intense high. Patients may also manipulate ER ta...

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Detalhes bibliográficos
Publicado no:Clin Drug Investig
Main Authors: Mayock, Stephen P., Saim, Said, Fleming, Alison B.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5684282/
https://ncbi.nlm.nih.gov/pubmed/28940174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40261-017-0561-9
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