Airborne particulate matter increases MUC5AC expression by downregulating Claudin-1 expression in human airway cells

CLB(2.0), a constituent of PM, induces secretion of multiple cytokines and chemokines that regulate airway inflammation. Specifically, IL-6 upregulates CLB(2.0)-induced MUC5AC and MUC1 expression. Interestingly, of the tight junction proteins examined, claudin-1 expression was inhibited by CLB(2.0)....

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Publicado en:BMB Rep
Autores principales: Kim, Sang-Su, Kim, Cheol Hong, Kim, Ji Wook, Kung, Hsi Chiang, Park, Tae Woo, Shin, Yu Som, Kim, Ju Deok, Ryu, Siejeong, Kim, Wang-Joon, Choi, Yung Hyun, Song, Kyoung Seob
Formato: Artigo
Lenguaje:Inglês
Publicado: Korean Society for Biochemistry and Molecular Biology 2017
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5683821/
https://ncbi.nlm.nih.gov/pubmed/28946937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5483/BMBRep.2017.50.10.100
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