IL-1ra Secreted by ATP-Induced P2Y(2) Negatively Regulates MUC5AC Overproduction via PLCβ3 during Airway Inflammation

Mucus secretion is often uncontrolled in many airway inflammatory diseases of humans. Identifying the regulatory pathway(s) of mucus gene expression, mucus overproduction, and hypersecretion is important to alleviate airway inflammation in these diseases. However, the regulatory signaling pathway co...

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Detalhes bibliográficos
Publicado no:Mediators Inflamm
Main Authors: Jeong, Jee-Yeong, Kim, Jiwook, Kim, Bokyoum, Kim, Joowon, Shin, Yusom, Kim, Judeok, Ryu, Siejeong, Yang, Yu-Mi, Song, Kyoung Seob
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4789511/
https://ncbi.nlm.nih.gov/pubmed/27034593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/7984853
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