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Synthesis and Application of Injectable Bioorthogonal Dendrimer Hydrogels for Local Drug Delivery
We developed novel dendrimer hydrogels (DH)s on the basis of bioorthogonal chemistry, in which polyamidoamine (PAMAM) dendrimer generation 4.0 (G4) functionalized with strained alkyne dibenzocyclooctyne (DBCO) via PEG spacer (M(n) = 2,000 g/mol) underwent strain-promoted azide-alkyne cycloaddition (...
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| Publicado no: | ACS Biomater Sci Eng |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5683721/ https://ncbi.nlm.nih.gov/pubmed/29147682 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsbiomaterials.7b00166 |
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