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Synthesis and Application of Injectable Bioorthogonal Dendrimer Hydrogels for Local Drug Delivery
We developed novel dendrimer hydrogels (DH)s on the basis of bioorthogonal chemistry, in which polyamidoamine (PAMAM) dendrimer generation 4.0 (G4) functionalized with strained alkyne dibenzocyclooctyne (DBCO) via PEG spacer (M(n) = 2,000 g/mol) underwent strain-promoted azide-alkyne cycloaddition (...
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| Publicado en: | ACS Biomater Sci Eng |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2017
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5683721/ https://ncbi.nlm.nih.gov/pubmed/29147682 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsbiomaterials.7b00166 |
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