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Inhibition of Allograft Inflammatory Factor-1 in Dendritic Cells Restrains CD4(+) T Cell Effector Responses and Induces CD25(+)Foxp3(+) T Regulatory Subsets
Allograft inflammatory factor-1 (AIF1) is a cytoplasmic scaffold protein shown to influence immune responses in macrophages and microglial cells. The protein contains Ca(2+) binding EF-hand and PDZ interaction domains important for mediating intracellular signaling complexes. This study now reports...
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| Publicado no: | Front Immunol |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5682305/ https://ncbi.nlm.nih.gov/pubmed/29167673 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01502 |
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