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CD40–CD40L cross-talk drives fascin expression in dendritic cells for efficient antigen presentation to CD4(+) T cells

Fascin is an actin-bundling protein that, among immune cells, is restricted to expression in dendritic cells (DCs). Previous reports have suggested that fascin plays an important role in governing DC antigen presentation to CD4(+) T cells. However, no report has clearly linked the receptor–ligand en...

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Detalhes bibliográficos
Publicado no:Int Immunol
Main Authors: Elizondo, Diana M., Andargie, Temesgen E., Kubhar, Dineeta S., Gugssa, Ayele, Lipscomb, Michael W.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5421612/
https://ncbi.nlm.nih.gov/pubmed/28369442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/intimm/dxx013
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