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RNA editing by ADAR1 leads to context-dependent transcriptome-wide changes in RNA secondary structure
Adenosine deaminase acting on RNA 1 (ADAR1) is the master RNA editor, catalyzing the deamination of adenosine to inosine. RNA editing is vital for preventing abnormal activation of cytosolic nucleic acid sensing pathways by self-double-stranded RNAs. Here we determine, by parallel analysis of RNA se...
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| Publicado no: | Nat Commun |
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| Main Authors: | , , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5682290/ https://ncbi.nlm.nih.gov/pubmed/29129909 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01458-8 |
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