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Physiological Levels of Nitric Oxide Diminish Mitochondrial Superoxide. Potential Role of Mitochondrial Dinitrosyl Iron Complexes and Nitrosothiols

Mitochondria are the major source of superoxide radicals and superoxide overproduction contributes to cardiovascular diseases and metabolic disorders. Endothelial dysfunction and diminished nitric oxide levels are early steps in the development of these pathological conditions. It is known that phys...

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Détails bibliographiques
Publié dans:Front Physiol
Auteurs principaux: Dikalov, Sergey I., Mayorov, Vladimir I., Panov, Alexander V.
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5681960/
https://ncbi.nlm.nih.gov/pubmed/29163230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2017.00907
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