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Reference-guided de novo assembly approach improves genome reconstruction for related species

BACKGROUND: The development of next-generation sequencing has made it possible to sequence whole genomes at a relatively low cost. However, de novo genome assemblies remain challenging due to short read length, missing data, repetitive regions, polymorphisms and sequencing errors. As more and more g...

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Detalles Bibliográficos
Publicado en:BMC Bioinformatics
Main Authors: Lischer, Heidi E. L., Shimizu, Kentaro K.
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5681816/
https://ncbi.nlm.nih.gov/pubmed/29126390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-017-1911-6
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