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Assisted assembly: how to improve a de novo genome assembly by using related species
We describe a new assembly algorithm, where a genome assembly with low sequence coverage, either throughout the genome or locally, due to cloning bias, is considerably improved through an assisting process via a related genome. We show that the information provided by aligning the whole-genome shotg...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
BioMed Central
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2745769/ https://ncbi.nlm.nih.gov/pubmed/19712469 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2009-10-8-r88 |
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