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The emergence of piRNAs against transposon invasion to preserve mammalian genome integrity

Transposable elements (TEs) contribute to the large amount of repetitive sequences in mammalian genomes and have been linked to species-specific genome innovations by rewiring regulatory circuitries. However, organisms need to restrict TE activity to ensure genome integrity, especially in germline c...

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Vydáno v:Nat Commun
Hlavní autoři: Ernst, Christina, Odom, Duncan T., Kutter, Claudia
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5681665/
https://ncbi.nlm.nih.gov/pubmed/29127279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01049-7
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