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The emergence of piRNAs against transposon invasion to preserve mammalian genome integrity

Transposable elements (TEs) contribute to the large amount of repetitive sequences in mammalian genomes and have been linked to species-specific genome innovations by rewiring regulatory circuitries. However, organisms need to restrict TE activity to ensure genome integrity, especially in germline c...

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Bibliographic Details
Published in:Nat Commun
Main Authors: Ernst, Christina, Odom, Duncan T., Kutter, Claudia
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5681665/
https://ncbi.nlm.nih.gov/pubmed/29127279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01049-7
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