Upregulation of microRNA-4417 and Its Target Genes Contribute to Nickel Chloride-promoted Lung Epithelial Cell Fibrogenesis and Tumorigenesis

Nickel compounds have been classified as carcinogens and shown to be associated with induction of epithelial-mesenchymal transition (EMT) in fibrogenesis and tumorigenesis, as well as the crucial role of microRNAs (miRNAs) and their related genes in controlling EMT and cancer metastasis. Thus, the m...

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Pubblicato in:Sci Rep
Autori principali: Wu, Chih-Hsien, Hsiao, Yi-Min, Yeh, Kun-Tu, Tsou, Tsui-Chun, Chen, Chih-Yi, Wu, Ming-Fang, Ko, Jiunn-Liang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5681645/
https://ncbi.nlm.nih.gov/pubmed/29127306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-14610-7
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