Deletion of hepatic carbohydrate response element binding protein (ChREBP) impairs glucose homeostasis and hepatic insulin sensitivity in mice

OBJECTIVE: Carbohydrate response element binding protein (ChREBP) is a transcription factor that responds to glucose and activates genes involved in the glycolytic and lipogenic pathways. Recent studies have linked adipose ChREBP to insulin sensitivity in mice. However, while ChREBP is most highly e...

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Bibliografske podrobnosti
izdano v:Mol Metab
Main Authors: Jois, Tara, Chen, Weiyi, Howard, Victor, Harvey, Rebecca, Youngs, Kristina, Thalmann, Claudia, Saha, Pradip, Chan, Lawrence, Cowley, Michael A., Sleeman, Mark W.
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2017
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5681238/
https://ncbi.nlm.nih.gov/pubmed/29107286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2017.07.006
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