PLOD2 regulated by transcription factor FOXA1 promotes metastasis in NSCLC

In multiple types of tumors, fibrotic collagen is regarded as the 'highway' for cancer cell migration, which is mainly modified by lysyl hydroxylase 2 (PLOD2). The previous findings have demonstrated that the expression of PLOD2 was regulated by multiple factors, including HIF-1α, TGF-β an...

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Veröffentlicht in:Cell Death Dis
Hauptverfasser: Du, Hongzhi, Chen, Yulong, Hou, Xiaoying, Huang, Yue, Wei, Xiaohui, Yu, Xiaowen, Feng, Shuyun, Wu, Yao, Zhan, Meixiao, Shi, Xin, Lin, Sensen, Lu, Ligong, Yuan, Shengtao, Sun, Li
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2017
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5680920/
https://ncbi.nlm.nih.gov/pubmed/29072684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.553
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