Dexamethasone mediates pancreatic cancer progression by glucocorticoid receptor, TGFβ and JNK/AP-1

Glucocorticoids such as dexamethasone are widely co-prescribed with cytotoxic therapy because of their proapoptotic effects in lymphoid cancer, reduction of inflammation and edema and additional benefits. Concerns about glucocorticoid-induced therapy resistance, enhanced metastasis and reduced survi...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Liu, Li, Aleksandrowicz, Ewa, Schönsiegel, Frank, Gröner, Daniel, Bauer, Nathalie, Nwaeburu, Clifford C, Zhao, Zhefu, Gladkich, Jury, Hoppe-Tichy, Torsten, Yefenof, Eitan, Hackert, Thilo, Strobel, Oliver, Herr, Ingrid
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5680577/
https://ncbi.nlm.nih.gov/pubmed/28981109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.455
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